钱海丰
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发布日期:2020-03-02
浏览次数:3085
工作经历: 2003 - 至今 浙江工业大学,威廉希尔,讲师(2003-2005)、副教授(2005-2010)、教授(2010-) 2018/1 - 2018/3 日本京都大学,农学部,JSPS BRIDGE项目 交流学者 2015年入选中科院百人计划 2015/2 - 2015/5 日本京都大学,农学部,访问学者 2012/7 - 2013/5,日本京都大学,农学部,JSPS研究员 2008/1 - 2008/6,美国康奈尔大学,作物与土壤科学系,博士后 1996/8 - 1998/8,绍兴文理学院,生化系,教师 学习经历: 1998/9 - 2003/7,浙江大学农学系,作物育种专业,硕博连读 1991/9 - 1996/7,中国海洋大学,海洋生物系本科
钱海丰,博士,教授,博士生导师,中科院百人,教育部创新团队成员,美国康奈尔大学博士后,日本京都大学JSPS 研究员;浙江省中青年学术骨干、中青年学术带头人。主持国家自然科学基金项目5 项,浙江省杰出青年基金等项目。主要从事环境毒理学与环境生态学研究。应用目前主流的分子生物学手段(如qRT-PCR、双向电泳,酶联免疫检测等)并结合组学概念(包括蛋白组学、基因组学、转录组等),从基因、蛋白、个体及群落结构等多层次、系统性分析:1)农药等污染物对植物的毒理,及其与土壤微生物之间的响应机制,了解胁迫环境下根际微生物群反馈调控植物生长发育的作用网络,阐述污染物-植物-环境微生物的三极关系;2)研究蓝藻水华诱发的水生态风险、水华蓝藻与水体微生物间的相互作用及信号传导途径,以及农药、抗生素等污染物对水生微生物群落结构和功能的安全评估。研究成果在ISME J, Microbiome, Environ Sci Technol, Environ Pollut, Environ Int, J Agric Food Chem, Appl Environ Microbio等发表SCI 论文100 余篇, SCI高引论文5篇。获授权国家发明专利5项。获“十一五”浙江省自然科学基金优秀论文奖1项、浙江省高校优秀科研成果奖一、二等奖各1项。 联系方式: Tel:13588450337 Email: hfqian@zjut.edu.cn;
一、主要承担项目 1. 国家重点研发计划项目,农业生物药物分子靶标发现与绿色药物分子设计,288万,2018/01-2021/12,参与。 2. 日本文部省JSPS BRIDGE项目资助(2018) 3. 国家自然科学基金面上项目,21777144,手性除草剂干扰土壤根系微生物群落结构及多样性的对映体选择性分析,2017/01-2020/12,64万,在研,主持。 4. 国家自然科学基金面上项目,21577128,典型人工纳米材料干扰拟南芥生长繁殖及其与除草剂的复合毒理,2016/01-2019/12,78万,在研,主持。 5. 浙江省自然科学杰出青年基金,LR14B070001,手性除草剂对拟南芥光合作用环式电子传递链的对映体选择性,2014/01-2016/12,36万,主持。 6. 教育部创新团队,IRT1309,生物净化与转化,2017/01-2019/12,300万,参与。 7. 国家自然科学基金面上项目,21277127,除草剂诱导根系有机酸分泌的特征及调控机理,2013/01-2016/12,80万,在研,主持。 8. 日本文部省JSPS项目资助(2012-2013),京都大学特别研究员 9. 国家自然科学基金面上项目,21077093,手性除草剂咪唑乙烟酸对拟南芥生物钟及其相关代谢功能调控的选择性差异研究,2011/01-2013/12,33万,结题,主持。 10. 浙江省钱江人才计划项目,2010R10033,自然环境因子下除藻化感物质的筛选及其分子毒理机制研究,2010/01-2012/12,10万,结题,主持。 11. 国家自然科学基金青年基金,20607020,手性除草剂对映体活性筛选及分子毒理机制的研究,2007/01-2009/12,25万,结题,主持。
二、近年来发表的主要论文 1. Zhou Z., Zhang Z., Feng L., Zhang J., Li Y., Lu T., Qian H (钱海丰, CA), Adverse effects of levo floxacin and oxytetracycline on aquatic microbial communities, Science of the Total Environment, 2020, 734. 2. Zhao Q., Liu W., Li Y., Ke M., Qu Q., Yuan W., Pan X., Qian H (钱海丰, CA), Enantioselective effects of imazethapyr residues on Arabidopsis thaliana metabolic profile and phyllosphere microbial communities, Journal of Environmental Sciences, 2020, 93: 57-65. 3. Liu W., Zhao Q., Zhang Z., Li Y., Xu N., Qu Q., Lu T., Pan X., Qian H (钱海丰, CA), Enantioselective effects of imazethapyr on Arabidopsis thaliana root exudates and rhizosphere microbes, Science of the Total Environment, 2020, 716. 4. Qu Q., Zhang Z., Peijnenburg WJGM., Liu W., Lu T., Hu B., Chen J., Chen J., Lin Z., Qian H (钱海丰, CA), Rhizosphere Microbiome Assembly and Its Impact on Plant Growth, Journal of Agricultural and Food Chemistry, 2020, 68: 5024-5038. 5. Lu T., Xu N., Zhang Q., Zhang Z., Debognies A., Zhou Z., Sun L., Qian H (钱海丰, CA), Understanding the influence of glyphosate on the structure and function of freshwater microbial community in a microcosm, Environmental Pollution, 2020, 260. 6. Wang X., Duo Y., He J., Yao J., Qian H (钱海丰)., Hrynsphan D., Tatsiana S., Chen J, A newly isolated and rapid denitrifier Pseudomonas citronellolis WXP-4: difference in N2O emissions under aerobic and anaerobic conditions, Bioprocess and Biosystems Engineering, 2020, 43: 811-820. 7. Ke M., Li Y., Qu Q., Ye Y., Peijnenburg WJGM., Zhang Z., Xu N., Lu T., Sun L., Qian H (钱海丰, CA), Offspring toxicity of silver nanoparticles to Arabidopsis thaliana flowering and floral development, Journal of Hazardous Materials, 2020, 386. 8. Lu T., Qu Q., Lavoie M., Pan X., Peijnenburg WJGM., Zhou Z., Pan X., Cai Z., Qian H (钱海丰, CA), Insights into the transcriptional responses of a microbial community to silver nanoparticles in a freshwater microcosm, Environmental Pollution, 2020, 258. 9. Qu Q., Zhang Z., Li Y., Zhou Z., Ye Y., Lu T., Sun L., Qian H (钱海丰, CA), Comparative molecular and metabolic responses of wheat seedlings (Triticum aestivum L.) to the imazethapyr enantiomers S-IM and R-IM, Science of the Total Environment, 2019, 692: 723-731. 10. Lu T., Zhou Z., Zhang Q., Zhang Z., Qian H (钱海丰, CA), Ecotoxicological Effects of Fungicides Azoxystrobin and Pyraclostrobin on Freshwater Aquatic Bacterial Communities, Bulletin of Environmental Contamination and Toxicology, 2019, 103: 683-688. 11. Zhang M., Lu T., Paerl H., Chen Y., Zhang Z., Zhou Z., Qian H (钱海丰, CA), Feedback Regulation between Aquatic Microorganisms and the Bloom-Forming Cyanobacterium Microcystis aeruginosa, Applied and Environmental Microbiology, 2019, 85. 12. Du B., Liu G., Ke M., Zhang Z., Zheng M., Lu T., Sun L., Qian H (钱海丰, CA), Proteomic analysis of the hepatotoxicity of Microcystis aeruginosa in adult zebrafish (Danio rerio) and its potential mechanisms, Environmental Pollution, 2019, 254. 13. Liu W., Ke M., Zhang Z., Lu T., Zhu Y., Li Y., Pan X., Qian H (钱海丰, CA), Effects of imazethapyr spraying on plant growth and leaf surface microbial communities in Arabidopsis thaliana, Journal of Environmental Sciences, 2019, 85: 35-45. 14. Zhang Q., Zhu D., Ding J., Zheng F., Zhou S., Lu T., Zhu Y., Qian H (钱海丰, CA), The fungicide azoxystrobin perturbs the gut microbiota community and enriches antibiotic resistance genes in Enchytraeus crypticus, Environment International, 2019, 131. 15. Lu T., Zhang Q., Lavoie M., Zhu Y., Ye Y., Yang J., Paerl, H., Qian H (钱海丰, CA)., Zhu Y, The fungicide azoxystrobin promotes freshwater cyanobacterial dominance through altering competition, Microbiome, 2019, 7. 16. Zhang Q., Zhu D., Ding J., Zhou S., Sun L., Qian H (钱海丰, CA), Species-specific response of the soil collembolan gut microbiome and resistome to soil oxytetracycline pollution, Science of the Total Environment, 2019, 668: 1183-1190. 17. Yang Z., Lu T., Zhu Y., Zhang Q., Zhou Z., Pan X., Qian H (钱海丰, CA), Aquatic ecotoxicity of an antidepressant, sertraline hydrochloride, on microbial communities, Science of the Total Environment, 2019, 654: 129-134. 18. Wang J., Hua M., Cai C., Hu J., Wang J., Yang H., Ma F., Qian H (钱海丰), Zheng P., Hua B., Spatial-temporal pattern of sulfate-dependent anaerobic methane oxidation in an intertidal zone of the east china sea, Applied and Environmental Microbiology, 2019, 85. 19. Liu H., Hu Z., Zhou M., Hu J., Yao X., Zhang H., Li Z., Lou L., Xi C., Qian, HF (钱海丰)., Li C., Xu X., Zheng P., Hu BL, The distribution variance of airborne microorganisms in urban and rural environments, Environmental Pollution, 2019, 247:898-906. 20. Qu Q., Ke M., Ye Y., Zhang Q., Lu T., Zhang Z., Qian H (钱海丰), Enantioselective Oxidative Stress Induced by S- and Rac-metolachlor in Wheat (Triticum aestivum L.) Seedlings, Bulletin of Environmental Contamination and Toxicology, 2019, 102:439-445. 21. Sun L., Gu L., Tan H., Liu P., Gao G.,Tian L., Chen H., Lu T., Qian H (钱海丰)., Fu Z., Pan X, Effects of 17 alpha-ethinylestradiol on caudal fin regeneration in zebrafish larvae, Science of the Total Environment, 2019, 653:11-22. 22. Du B., Zhang Z., Liu W., Ye Y., Lu T., Zhou Z., Li Y., Fu Z., Qian H (钱海丰, CA), Acute toxicity of the fungicide azoxystrobin on the diatom Phaeodactylum tricornutum, Ecotoxicology and Environmental Safety, 2019, 168: 72-79. 23. Qian H (钱海丰, CA), Zhang M., Liu G., Lu T., Sun L., Pan X., Effects of different concentrations of Microcystis aeruginosa on the intestinal microbiota and immunity of zebrafish (Danio rerio), Chemosphere, 2019, 214: 579-586. 24. Lu T., Zhu Y., Ke M., Peijnenburg W. J. G. M., Zhang M., Wang T., Chen J., Qian H (钱海丰, CA), Evaluation of the taxonomic and functional variation of freshwater plankton communities induced by trace amounts of the antibiotic ciprofloxacin, Environment International, 2019, 268-278. 25. Zhang Z., Ke M., Qu Q., Peijnenburg W. J. G. M., Lu T., Zhang Q., Ye Y., Xu P., Du B., Sun L., Qian H (钱海丰, CA), Impact of copper nanoparticles and ionic copper exposure on wheat (Triticum aestivum L.) root morphology and antioxidant response, Environmental Pollution, 2018, 239: 689-697. 26. Zhang Q., Qu Q., Lu T., Ke M., Zhu Y., Zhang M., Zhang Z., Du B., Pan X., Sun L., Qian H (钱海丰, CA), The combined toxicity effect of nanoplastics and glyphosate on Microcystis aeruginosa growth, Environmental Pollution, 2018, 243: 1106-1112. 27. Qian H (钱海丰, CA), Xu J., Lu T., Zhang Q., Qu Q., Yang Z., Pan X., Responses of unicellular alga Chlorella pyrenoidosa to allelochemical linoleic acid, Science of the Total Environment, 2018, 625: 1415-1422. 28. Lu T., Zhu Y., Xu J., Ke M., Zhang M., Tan C., Fu Z., Qian H (钱海丰, CA), Evaluation of the toxic response induced by azoxystrobin in the non-target green alga Chlorella pyrenoidosa, Environmental Pollution, 2018, 234: 379-388. 29. Lu T., Ke M., Peijnenburg W. J. G. M., Zhu Y., Zhang M., Sun L., Fu Z., Qian H (钱海丰, CA), Investigation of Rhizospheric Microbial Communities in Wheat, Barley, and Two Rice Varieties at the Seedling Stage, Journal of Agricultural and Food Chemistry, 2018, 66: 2645-2653. 30. Lu T., Ke M., Lavoie M., Jin Y., Fan X., Zhang Z., Fu Z., Sun L., Gillings M., Pe?uelas J., Qian H (钱海丰, CA), Zhu Y. G. (CA), Rhizosphere microorganisms can influence the timing of plant flowering, Microbiome, 2018, 6. 31. Liu G., Ke M., Fan X., Zhang M., Zhu Y., Lu T., Sun L., Qian H (钱海丰, CA), Reproductive and endocrine-disrupting toxicity of Microcystis aeruginosa in female zebrafish, Chemosphere, 2018, 192: 289-296. 32. Li X., Ke M., Zhang M., Peijnenburg W. J. G. M., Fan X., Xu J., Zhang Z., Lu T., Fu Z., Qian H (钱海丰, CA), The interactive effects of diclofop-methyl and silver nanoparticles on Arabidopsis thaliana: Growth, photosynthesis and antioxidant system, Environmental Pollution, 2018, 232: 212-219. 33. Ke M., Qu Q., Peijnenburg W. J. G. M., Li X., Zhang M., Zhang Z., Lu T., Pan X., Qian H (钱海丰, CA), Phytotoxic effects of silver nanoparticles and silver ions to Arabidopsis thaliana as revealed by analysis of molecular responses and of metabolic pathways, Science of the Total Environment, 2018, 644: 1070-1079. 34. Fan X., Xu J., Lavoie M., Peijnenburg W. J. G. M., Zhu Y., Lu T., Fu Z., Zhu T., Qian H (钱海丰, CA), Multiwall carbon nanotubes modulate paraquat toxicity in Arabidopsis thaliana, Environmental Pollution, 2018, 233: 633-641. 35. Song H., Lavoie M., Fan X., Tan H., Liu G., Xu P., Fu Z., Paerl H. W., Qian H (钱海丰, CA), Allelopathic interactions of linoleic acid and nitric oxide increase the competitive ability of Microcystis aeruginosa, Isme Journal, 2017, 11: 1865-1876. 36. Jin Y., Fan X., Li X., Zhang Z., Sun L., Fu Z., Lavoie M., Pan X., Qian H (钱海丰, CA), Distinct physiological and molecular responses in Arabidopsis thaliana exposed to aluminum oxide nanoparticles and ionic aluminum, Environmental Pollution, 2017, 228: 517-527. 37. Asad M. A. U., Lavoie M., Song H., Jin Y., Fu Z., Qian H (钱海丰, CA), Interaction of chiral herbicides with soil microorganisms, algae and vascular plants, Science of the Total Environment, 2017, 580: 1287-1299. 38. Sun C., Chen S., Jin Y., Song H., Ruan S., Fu Z., Asad M. A. U., Qian H (钱海丰, CA), Effects of the herbicide imazethapyr on photosynthesis in PGR5- and NDH-deficient arabidopsis thaliana at the biochemical, transcriptomic, and proteomic levels, Journal of Agricultural and Food Chemistry, 2016, 64: 4497-4504. 39. Qian H (钱海丰, CA), Zhu K., Lu H., Lavoie M., Chen S., Zhou Z., Deng Z., Chen J., Fu Z., Contrasting silver nanoparticle toxicity and detoxification strategies in Microcystis aeruginosa and Chlorella vulgaris: New insights from proteomic and physiological analyses, Science of the Total Environment, 2016, 572: 1213-1221. 40. Bai X., Song H., Lavoie M., Zhu K., Su Y., Ye H., Chen S., Fu Z., Qian H (钱海丰, CA), Proteomic analyses bring new insights into the effect of a dark stress on lipid biosynthesis in Phaeodactylum tricornutum, Scientific Reports, 2016, 6. 41. Xie J., Bai X., Lavoie M., Lu H., Fan X., Pan X., Fu Z., Qian H (钱海丰, CA), Analysis of the Proteome of the Marine Diatom Phaeodactylum tricornutum Exposed to Aluminum Providing Insights into Aluminum Toxicity Mechanisms, Environmental Science and Technology, 2015, 49: 11182-11190. 42. Sun C., Jin Y., He H., Wang W., He H., Fu Z., Qian H (钱海丰, CA), Two novel herbicide candidates affect Arabidopsis thaliana growth by inhibiting nitrogen and phosphate absorption, Pesticide Biochemistry and Physiology, 2015, 123: 1-8. 43. Qian H (钱海丰)., Wei Y., Bao G., Huang B., Fu Z., Atrazine affects the circadian rhythm of microcystis aeruginosa, Chronobiology International, 2014, 31: 17-26. 44. Qian H (钱海丰, CA), Tsuji T., Endo T., Sato F., PGR5 and NDH pathways in photosynthetic cyclic electron transfer respond differently to sublethal treatment with photosystem-interfering herbicides, Journal of Agricultural and Food Chemistry, 2014, 62: 4083-4089. 45. Ding H., Lu H., Lavoie M., Xie J., Li Y., Lv X., Fu Z., Qian H (钱海丰, CA), Unraveling the toxicity mechanisms of the herbicide diclofop-methyl in rice: Modulation of the activity of key enzymes involved in citrate metabolism and induction of cell membrane anion channels, Journal of Agricultural and Food Chemistry, 2014, 62: 10654-10660. 46. Qian H (钱海丰)., Han X., Zhang Q., Sun Z., Sun L., Fu Z., Imazethapyr enantioselectively affects chlorophyll synthesis and photosynthesis in arabidopsis Thaliana, Journal of Agricultural and Food Chemistry, 2013, 61: 1172-1178. 47. Zhang Q., Zhao M., Qian H (钱海丰)., Lu T., Zhang Q., Liu W., Enantioselective damage of diclofop acid mediated by oxidative stress and acetyl-CoA carboxylase in nontarget plant Arabidopsis thaliana, Environmental Science and Technology, 2012, 46: 8405-8412. 48. Qian H (钱海丰)., Wang R., Chen J., Ding H., Yong W., Songlin R., Fu Z., Analysis of enantioselective biochemical, physiological, and transcriptional effects of the chiral herbicide diclofop methyl on rice seedlings, Journal of Agricultural and Food Chemistry, 2012, 60: 5515-5523. 49. Qian H (钱海丰)., Wang R., Hu H., Lu T., Chen X., Ye H., Liu W., Fu Z., Enantioselective phytotoxicity of the herbicide imazethapyr and its effect on rice physiology and gene transcription, Environmental Science and Technology, 2011, 45: 7036-7043.
三、教材: 钱海丰,裘娟萍主编。《生命科学概论》,科学出版社,2016年 郑平,胡宝兰,吕镇梅,钱海丰等(译)。《生物技术》,科学出版社,2006年 裘娟萍,钱海丰主编。《生命科学概论》,科学出版社,2004年
四、科研成果及专利: (1) 钱海丰,白小翠,魏勇,傅正伟,一种提高三角褐指藻脂质积累的培养方法,CN201410092191.9。 (2) 钱海丰,白小翠,孙冲冲,魏勇,傅正伟,Fe在缓解Cu对三角褐指藻细胞毒害中的应用,CN201410154370.0。 (3) 钱海丰,丁海燕,傅正伟,无外界动力推动的离子交换树脂层析方法及装置, CN201310394008.6。 (4) 钱海丰,余澍琼,傅正伟,过氧化氢在制备微囊藻毒素抑制剂中的应用,CN201110032486.3。 (5) 钱海丰,丁海燕,傅正伟,无外界动力推动的离子交换树脂层析装置, CN201320542803.0。
五、研究生培养等教学情况: 已培养2篇省优秀硕士论文,3位省优秀毕业生。
六、获奖情况: 获“十一五”浙江省自然科学基金优秀论文奖1项 浙江省高校优秀科研成果奖一、二等奖各1项 |
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